Overview

With contemporary chemotherapy, the overall survival rate for childhood cancer is increasing with current 5-year survival rates >85%; however, survivors of childhood cancer are at increased risk for morbidity and early mortality due to late effects of their treatment. Our group’s goal is to improve the overall health and quality of life of pediatric cancer survivors through early detection and treatment of late effects. Our main areas of focus are how to improve lifestyle behaviors in survivors, the use of technology to improve care delivery, and transitions of care.  

  • Improving Support for Survivors Engaged in Transition (IS SET) 
  • Developing a Wellness Intervention for Adolescent Childhood Cancer Survivors  
  • Evaluation of Vestibular Dysfunction in Survivors of Childhood and Adolescent Cancer Treated with Platinum-Based Chemotherapies 
  • The Future of SCPs (Survivorship Care Plans) 

Sanyukta Janardan, MD, MS (Assistant Professor of Pediatrics)

Education: Emory University Pediatric Hematology/Oncology Fellow, 2019-2022

Current Projects: A pre-pilot study of the feasibility and acceptability of a targeted health education intervention in childhood cancer survivors at high risk for therapy-related adverse cardiovascular events

sjanard@emory.edu

 

Liberty Strange, MD, MPH  (Pediatric Hematology/Oncology Survivor Fellow) 

Education: Emory University Pediatric Hematology/Oncology Fellow, 2022-2024

Current Projects: Investigating Rurality and its Association with  Childhood Cancer Survivor Car; Impact of Rurality on Healthcare Utilization, Health Behaviors, and Health Status of Childhood Cancer Survivors 

lfstran@emory.edu

 

Zahra Jiwani, MD (Pediatric Hematology/Oncology Fellow) 

Education: Emory University Pediatric Hematology/Oncology Fellow, 2023-2025

Current Projects: Impact of Structural Racism and Psychosocial Services Utilization on Pediatric Cancer Survivor Care 

zahra.merchant.jiwani@emory.edu

Aaron Wallace, MD, 2019-2020, Emory University Medical Student

Current position: Pediatric Resident, Maine Medical Center

Kirsten Rose-Felker, MD, 2016-2018, Pediatric Cardiology Fellow

Current position: Faculty, University of Pittsburgh

Zachary Owens, MPH, 2016-2017, Rollins School of Public Health MPH Student

Current position: Medical Resident, Emory University School of Medicine 

Ashley Eason, MD, 2017-2019, Pediatric Hematology/Oncology Fellow

Current position: Pediatric Hematologist/Oncologist, Memorial Health University, Savannah, Georgia

Emily Silverman, 2018-2019, Emory University Undergraduate

Current position: Clinical Research Associate, Brigham and Women’s Hospital

  • Section Leader, Children’s Oncology Group Long-term Follow-up Guidelines Oral/Dental/Gastrointestinal/Hepatic and Urinary Tract Task Forces
  • Institutional Principal Investigator, Childhood Cancer Survivor Study

Ji X, Cummings JR, Mertens AC, Wen H, Effinger KE. Substance use, substance use disorders, and treatment in adolescent and young adult cancer survivors-Results from a national survey. Cancer. 2021 Sep 1;127(17):3223-3231. doi: 10.1002/cncr.33634. Epub 2021 May 11. PMID: 33974717.

Bardi E, Mulder RL, van Dalen EC, Bhatt NS, Ruble KA, Burgis J, Castellino SM, Constine LS, den Hoed CM, Green DM, Koot BGP, Levitt G, Szonyi L, Wallace WH, Skinner R, Hudson MM, Kremer LCM, Effinger KE, Bresters D. Late hepatic toxicity surveillance for survivors of childhood, adolescent and young adult cancer: Recommendations from the international late effects of childhood cancer guideline harmonization group. Cancer Treat Rev. 2021 Nov;100:102296. doi: 10.1016/j.ctrv.2021.102296. Epub 2021 Sep 20. PMID: 3457137.

Ji X, Hu X, Brock KE, Mertens AC, Cummings JR, Effinger KE. Early Posttherapy Opioid Prescription, Potential Misuse, and Substance Use Disorder Among Pediatric Cancer Survivors. J Natl Cancer Inst. 2022 Jun 13;114(6):895-906. doi: 10.1093/jnci/djac049. PMID: 35262708; PMCID: PMC9194632.

Marchak JG, Kegler MC, Meacham LR, Mertens AC, Effinger KE. Cancer-Related Barriers to Health Behaviors Among Adolescent and Young Adult Survivors of Pediatric Cancer and Their Families. J Adolesc Young Adult Oncol. 2023 Feb;12(1):118-122. doi: 10.1089/jayao.2021.0169. Epub 2022 Mar 21. PMID: 35325580.

Marchak JG, Sadak KT, Effinger KE, Haardörfer R, Escoffery C, Kinahan KE, Freyer DR, Chow EJ, Mertens A. Transition practices for survivors of childhood cancer: a report from the Children's Oncology Group. J Cancer Surviv. 2023 Apr;17(2):342-350. doi: 10.1007/s11764-023-01351-y. Epub 2023 Mar 4. PMID: 36870037; PMCID: PMC9984742.

Effinger KE, Haardörfer R, Gilleland Marchak J, Escoffery C, Landier W, Kommajosula A, Hendershot E, Sadak KT, Eshelman-Kent D, Kinahan K, Freyer DR, Chow EJ, Mertens AC. Current Pediatric Cancer Survivorship Practices: A Report from the Children’s Oncology Group. Journal of Cancer Survivorship. 2023 Aug; 17(4): 1139-1148.

Border WL, Effinger KE, Leger KJ. How Best to Predict Who Will Develop Left Ventricular Dysfunction in Childhood Cancer Survivors: The Search for the Echocardiography “Holy Grail.” Journal of American College of Cardiology: Cardiooncology. 2023 Aug; 5(4):486-488.

 

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Federally Funded: 

NIH: R01 - 2022-2026

Personalized Risk Prediction to Reduce Cardiovascular Disease in Childhood Cancer Survivors

Role: Co-I

PI: Howell 

 

NIH: R61 - 2022-2027

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Bone Sarcoma

Role: Site PI

PI: Brinkman 

 

Private Foundation Funded: 

Woodruff Health Sciences Center Synergy Grant - 2021-2024

Developing a Wellness Intervention for Adolescent Childhood Cancer Survivors 

MPI: Effinger, Marchak, Kegler 

 

Imlay Foundation: Imlay Innovation Award - 2022-2024

The Future of SCPs (Survivorship Care Plans)

MPI: Effinger, Wang

 

PROTEUS Consortium & Pfizer Global Medical Grant - 2023-2025

Supporting Electronic Evaluation of Symptoms for Anxiety and Depression After Childhood Cancer Treatment

Role: Co-I

PI: Marchak

 

Aflac Cancer & Blood Disorders Center Pilot Award - 2022-2024

Opioids and Alternatives for Pain Management in Adolescent and Young Adult Survivors of Childhood Cancer: A Mixed Methods Approach 

Role: Co-I

PI: Ji