The CARRA-Arthritis Foundation Large Grant is intended to support established investigators in initiating, advancing, or expanding innovative research projects that further basic, clinical, or translational research and align with the CARRA mission, 2026–2028 Strategic Plan, and Research Agenda. 

Eligibility 

• The project principal investigator (PI) for all grants must be a current CARRA member who is up to date on membership dues and has ensured their membership information is current and accurate.
• Previous and current CARRA awardees who wish to submit new grant applications must be up to date on all award deliverables.
• Applicants must hold an advanced degree (MD or equivalent, PhD, or MD/PhD) and must have a faculty or equivalent government appointment.
• All applications must be submitted by or include a pediatric rheumatologist named as a coinvestigator (co-I).
• The following current CARRA members are eligible to serve as Principal Investigators:
  • Pediatric rheumatologists
  • Other physicians and health care professionals
  • Research professionals (e.g., research scientists, investigators, and coordinators), excluding regulatory coordinators and data coordinators
• While not eligible to serve as PIs, the following may serve as team members: medical and graduate students, research professional members who are regulatory or data coordinators, business and industry associate members, and nonprofit/government associate members.
• CARRA board members or those in executive leadership positions may not serve as study leadership.