Dr. Spector studies the causes of childhood cancer with a focus on leukemia, bone sarcomas, and hepatoblastoma.  In his work he uses surveillance data, traditional case-control studies examining environmental and lifestyle risk factors, and genetic epidemiologic approaches. Regarding the latter, Dr. Spector uses both array and next-generation sequencing data to understand the germline basis of childhood cancer risk; his modes of analysis include genomewide association studies, transcriptome-wide association studies, gene burden analyses, de novo mutation analysis, and admixture mapping. The ultimate goal of Dr. Spector’s research is to enable the prediction, early detection, and, eventually, prevention of childhood cancer

Dr Spector will present "Towards a Complete Genetic Architecture For Childhood Acute Lymphoblastic Leukemia"