"Mapping Disease Biology with Translational Bioinformatics and Integrative Multi-Omics"

Diego Moncada-Giraldo, Ph.D., is a Scientist (Assistant Bioinformatics) in the Department of Pediatrics at Emory University. He integrates multi-omics and high-dimensional immune profiling—including bulk and single-cell transcriptomics, spatial approaches, proteomics/metabolomics, and advanced flow cytometry—with rigorous computational modeling to define disease-relevant myeloid cell states in the lung.

His research centers on neutrophil and monocyte plasticity in cystic fibrosis and infection-associated lung inflammation, with the goal of enabling host-directed strategies that restore antimicrobial function while limiting tissue-damaging inflammation. Dr. Moncada-Giraldo has contributed to peer-reviewed publications in Nature, Journal of Clinical Investigation, and Cell Reports Medicine, and collaborates closely with clinical and translational teams to connect mechanistic immune programs to therapeutic target discovery.