Carlton D. Dampier, MD
Institutional Review Board (IRB) Chair,
Aflac Cancer & Blood Disorders Center
Children’s Healthcare of Atlanta
Professor of Pediatrics,
Emory University School of Medicine
Primary research interest and efforts: My broad research interest is the assessment of patient-reported outcomes and subsequent symptom management in children and adolescents, particularly those with pain from sickle cell disease. I have led or participated in a number of studies validating specific assessment tools, as well as longitudinal observation studies examining symptom frequency by self-report or parent-proxy reporting. I have led or participated in a number of clinical trials of analgesics or investigational drugs for the treatment of vaso-occlusive sickle cell pain. As a research administrator, I have a broad interest in process improvement and quality management of clinical trials, as well as research ethics and scientific integrity in the conduct of clinical trials. Primary/current project focus: I currently have two major projects. I am the Network Chair and Protocol co-director for a NIH-funded multi-center randomized clinical trial of Patient-controlled analgesia in children and adults hospitalized for pain management. This is part of my ongoing efforts to develop multi-center pain-related clinical trials in SCD. I also have continued my interest in symptom assessment, and I am funded to participate in the NIH-funded Patient Reported Outcomes Information System (PROMIS), which is developing and validating the next-generation of symptom and health-related quality of life tools. I am also collaborating with other investigators on projects developing assessment tools for physical recovery and other functional outcomes for use in patient management or clinical trials. Collaborations: NIH/NHLBI Sickle Cell Disease Clinical Trial Network U10 HL083705-05 4/1/06-3/31/11Dr Dampier is the Chair of this Network from 4/1/08 until 3/31/11. Atlanta Clinical and Translational Science Institute U54 RR 024380-03 (Stephens, Emory) 09/30/07 - 09/29/12 This NIH/NCRR-CTSA grant award supports the Atlanta Clinical and Translational Science Institute. Dr Dampier is the Program Director for the Ethics, Regulatory Knowledge, and Support Component, and Co-Director of the Pediatric component of the program.