Research
Our research seeks to understand the fundamental transcriptional and epigenetic mechanisms that govern immune responses with both B cells and T cells. Our models include B cell differentiation pathways that lead to the molecular programming of plasma cells; T cell activation mechanisms and the regulation of the PD-1 gene; and dysregulation of immune cell programming in autoimmune diseases such as systemic lupus erythematosus.
Research Interest Keywords
Immune responses, CRISPR, gene editing, epigenetics, autoimmunity