Faculty Directory

William T. Mahle, MD

William T. Mahle, MD headshot

Division Director of Pediatric Cardiology, Professor of Pediatrics, Emory University School of Medicine

Director of Clinical Research Program. Pediatric Cardiologist, Children’s Healthcare of Atlanta

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PHONE: 404-256-2593

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William Mahle, MD, is the Chief of Cardiology at Children’s Healthcare of Atlanta Heart Center and is the Marcus Professor and Division Director of Cardiology, Department of Pediatrics, Emory University School of Medicine. His academic interests have focused on perioperative care with a particular interest in neurodevelopmental outcomes. Dr. Mahle is committed to research in the field of pediatric cardiology and congenital heart disease. He serves on several national committees including National Heart Lung and Blood Institute (NHLBI), Pediatric Heart Network (PHN), American Heart Association’s Cardiovascular Disease in the Young (CVDY), and United Network Organ Sharing (UNOS).

Dr. Mahle graduated from Yale University, attended medical school at the University of Maryland and completed his pediatric residency at the Children’s Hospital of Philadelphia. Following his pediatric cardiology fellowship at the Children’s Hospital of Philadelphia in 1999, he did an advanced fellowship in non-invasive imaging. In 2001, he joined the pediatric cardiology team at Emory University School of Medicine. In 2013, he was awarded the Marcus Professor in Pediatric Cardiology. Dr. Mahle is the Medical Director of the Heart Transplant and Heart Failure Service at Children’s Healthcare of Atlanta. He is Vice Chair on the United Network of Organ Sharing (UNOS) Pediatric Committee, Chair on the American Heart Association Council on Cardiovascular Disease in the Young, and on the Executive committee of the American Academy of Pediatric Section on Cardiology and Cardiac Surgery (SOCCS).


Dr. Mahle’s research interests include systems improvement using novel industrial engineering approaches. He has extensive experience with clinical trials. He is the study chair for the NHLBI PumpKIN trial evaluating pediatric-specific mechanical support devices. Dr. Mahle is also the site PI for a number of clinical trials in heart transplantation funded by the National Institutes of Health (NIH). He also directs the neurodevelopmental outcome clinical and research program that is focused on improving developmental outcomes and functional abilities of children and adolescents with congenital heart disease.  This program employed state-of-the-art brain imaging, including functional MRI to understand the impairments in memory and attention that are common following congenital heart surgery.

Research Areas of Interest

  • Heart Transplantation
  • Outcomes research in congenital heart disease, neurodevelopmental outcomand es, pediatric heart transplantation.
  • Research interests are focused on optimizing developmental status for children with congenital heart disease.


Medical Degree

  • University of Maryland School of Medicine, Baltimore, MD


  • Pediatrics, The Children’s Hospital of Philadelphia, Philadelphia, PA


  • Pediatric Cardiology, The Children’s Hospital of Philadelphia, Philadelphia, PA
  • Advanced Fellowship in Non-invasive Imaging, The Children’s Hospital of Philadelphia, Philadelphia, PA

Research Center(s)